TETRAPEPTIDE-16 is graded A (Safe) by Expert·ING, based on COSING, FDA regulatory data.

TETRAPEPTIDE-16

Safety grade: A

This is a small chain of amino acids (the building blocks of proteins) created in a laboratory. It works to help improve skin's texture and appearance by supporting the skin's natural structure.

Tetrapeptide-16 is used in skincare products to condition and improve skin feel, helping to soften the skin and enhance its overall smoothness and hydration.

Graded using: COSING, FDA.

Last verified: May 26, 2026