SH-POLYPEPTIDE-53 is graded A (Safe) by Expert·ING, based on COSING regulatory data.

SH-POLYPEPTIDE-53

Safety grade: A

This is a specially engineered protein fragment made up of amino acids linked together in a chain. It's designed to help improve skin texture and maintain skin health by supporting the skin's natural structure.

This ingredient conditions and protects the skin by helping to maintain moisture, improve elasticity, and support the skin barrier function for a smoother, healthier-looking complexion.

Graded using: COSING.

Last verified: May 26, 2026