SH-POLYPEPTIDE-45 is graded A (Safe) by Expert·ING, based on COSING regulatory data.
SH-POLYPEPTIDE-45
Safety grade: A
This is a lab-created protein fragment made up of amino acids (the building blocks of proteins) designed to improve skin health. It works by penetrating the skin to support its natural structure and moisture balance.
This ingredient conditions and moisturizes the skin by helping to strengthen the skin barrier and improve hydration levels.
Graded using: COSING.
Last verified: May 26, 2026
Other Skin Conditioning ingredients
- TOCOPHEROL — Grade A
- PROPYLENE GLYCOL — Grade A**
- XANTHAN GUM — Grade A
- DIMETHICONE — Grade A
- TOCOPHERYL ACETATE — Grade A
- PANTHENOL — Grade A
- CAPRYLYL GLYCOL — Grade A
- ETHYLHEXYLGLYCERIN — Grade A