RH-POLYPEPTIDE-45 is graded F (Banned) by Expert·ING, based on COSING regulatory data. It is restricted under EU COSING — AnnexII.

RH-POLYPEPTIDE-45

Safety grade: F

This is a laboratory-created protein fragment made up of amino acids linked together in a specific chain. It works to help improve skin texture and appearance by providing conditioning benefits.

This ingredient conditions and softens the skin by helping to improve hydration and the overall feel of the skin surface.

Graded using: COSING.

Last verified: May 26, 2026

Other EU Prohibited (Annex II) ingredients

Other Skin Conditioning ingredients