R-CLOSTRIDIUM HISTOLYTICUM COLLAGENASE H HEXAPEPTIDE-40 is graded A (Safe) by Expert·ING, based on COSING regulatory data.

R-CLOSTRIDIUM HISTOLYTICUM COLLAGENASE H HEXAPEPTIDE-40

Collagenase Hexapeptide-40

Safety grade: A

This is a lab-created ingredient derived from a bacterial enzyme that helps break down and remodel collagen in the skin. It's designed to improve skin texture and appearance by working on the skin's structural proteins.

This ingredient conditions and rejuvenates skin by enzymatically breaking down damaged collagen fibers, promoting skin renewal and improving firmness and elasticity.

Graded using: COSING.

Last verified: May 26, 2026

Other Skin Conditioning ingredients

TOCOPHEROL — Grade A
PROPYLENE GLYCOL — Grade A**
XANTHAN GUM — Grade A
DIMETHICONE — Grade A
TOCOPHERYL ACETATE — Grade A
PANTHENOL — Grade A
CAPRYLYL GLYCOL — Grade A
ETHYLHEXYLGLYCERIN — Grade A