POLOXAMINE 504 is graded A (Safe) by Expert·ING, based on COSING regulatory data.

POLOXAMINE 504

Safety grade: A

Poloxamine 504 is a man-made helper ingredient that works like a bridge between water and oils. It allows products that normally don't mix together—like water and oil—to blend smoothly into a single, stable product.

This ingredient stabilizes cosmetic formulas by helping water and oil-based components mix together evenly, creating smooth, uniform products that won't separate over time.

Graded using: COSING.

Last verified: May 26, 2026