PENTAPEPTIDE-21 is graded A (Safe) by Expert·ING, based on COSING regulatory data.

PENTAPEPTIDE-21

Safety grade: A

Pentapeptide-21 is a small chain of amino acids (the building blocks of proteins) that is designed to help improve skin texture and firmness. It works by signaling skin cells to produce more collagen and elastin, the proteins that keep skin looking youthful and elastic.

This ingredient is used in skincare products to condition and improve the appearance of skin by promoting natural protein production that enhances skin firmness, smoothness, and overall quality.

Graded using: COSING.

Last verified: May 26, 2026