R-SPIDER POLYPEPTIDE-2 is graded A (Safe) by Expert·ING, based on COSING regulatory data.

R-SPIDER POLYPEPTIDE-2

Spider Silk Polypeptide

Safety grade: A

This is a protein derived from spider silk that mimics the strengthening properties of natural silk fibers. It works to fortify and protect hair, nails, and skin similar to how silk proteins condition and protect fibers.

This ingredient strengthens and conditions hair and nails while forming a protective barrier on the skin to help retain moisture and improve overall resilience.

Graded using: COSING.

Last verified: May 26, 2026

Other Nail Conditioning ingredients

COMMIPHORA MYRRHA RESIN EXTRACT — Grade A
ECHINACEA ANGUSTIFOLIA ROOT EXTRACT — Grade A
VACCINIUM MYRTILLUS LEAF EXTRACT — Grade A
2-METHYLPROPANAL — Grade A**
4,4'-ISOPROPYLIDENEDIPHENYL/EPICHLOROHYDRIN COPOLYMER DIACRYLATE — Grade A
ACETALDEHYDE — Grade F**
ACRYLIC ACID — Grade A**
AMP-ISOSTEAROYL HYDROLYZED SILK — Grade B