PENTAPEPTIDE-48 is graded A (Safe) by Expert·ING, based on COSING regulatory data.

PENTAPEPTIDE-48

Safety grade: A

A lab-created protein fragment designed to help smooth and firm the skin's appearance. It works by signaling skin cells to boost collagen production, which may reduce the look of fine lines and improve skin texture over time. This ingredient is commonly found in anti-aging serums and creams.

Graded using: COSING.

Last verified: June 9, 2026