HEXAPEPTIDE-81 is graded A (Safe) by Expert·ING, based on COSING regulatory data.

HEXAPEPTIDE-81

Safety grade: A

A lab-created protein fragment designed to help relax facial muscles and reduce the appearance of fine lines and wrinkles. It works similarly to other anti-aging peptides by signaling skin to soften expression lines, particularly on the forehead and around the eyes.

Graded using: COSING.

Last verified: June 9, 2026