HEXAPEPTIDE-104 is graded A (Safe) by Expert·ING, based on COSING regulatory data.

HEXAPEPTIDE-104

Safety grade: A

A lab-created protein fragment designed to help relax facial muscles and reduce the appearance of fine lines and wrinkles. It works by signaling skin to soften expression lines, similar to how other anti-aging peptides function. Commonly found in serums and creams targeting forehead wrinkles and crow's feet.

Graded using: COSING.

Last verified: June 9, 2026