4-METHYL-M-PHENYLENEDIAMINE (TOLUENE-2,4-DIAMINE) AND ITS SALTS is graded F (Banned) by Expert·ING, based on EU COSING Annex II regulatory data. It is restricted under EU COSING — AnnexII.

4-METHYL-M-PHENYLENEDIAMINE (TOLUENE-2,4-DIAMINE) AND ITS SALTS

Safety grade: F

This chemical is prohibited in EU cosmetics because it is classified as carcinogenic (Category 1B) and mutagenic (Category 2) and toxic to reproduction (Category 2) under EU CLP Regulation. CMR substances are chemicals that can cause cancer, genetic mutations, or harm to reproductive health. The EU bans all CMR Category 1A, 1B, and 2 substances from cosmetic products under COSING Annex II.

Graded using: EU COSING Annex II.

• EU COSING — Prohibited
• Health Canada — Prohibited

Last verified: June 7, 2026